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Stanozolol(Winstrol) is an extremely popular anabolic-androgenic steroid(AAS), that is primarily used to improve physique, athletic performance and strength. Stanozolol(Winstrol) is considered to have a more powerful anabolic- to-androgenic effect when compared to testosterone, which makes purchasing Stanazol for sale on our site popular among performance-athletes.
A derivative of dihydrotestosterone(DHT), stanozolol(Winstrol) has been medically used to treat hereditary angioedema, venous insufficiency, osteoporosis, and skeletal muscle injury.
Stanozolol’s(Winstrol) mechanism of action is unique. Its primary operation is through binding with the androgen receptor rather than non-receptor mediated activity, which is common with AAS, such as Dianabol or Anadrol. Stanozolol(Winstrol) also has a low affinity for binding with the glucocorticoid binding-sites, in addition to some activity that is independent of androgen receptors. Stanozolol(Winstrol) also possesses a very low degree of progestogenic activity in the body.
Stanozolol(Winstrol) has a high oral bioavailability due to a C17α alkylation, which allows the hormone to survive first-pass liver metabolism when ingested. Because the hormone can survive the the first-pass liver metabolism, stanozolol(Winstrol) is offered in tablet form. Purchasing Stanazol for sale from PrecisionAnabolcs in tablet form, is often the first-choice for those who are new to using anabolic-androgenic steroid’s(AAS), in order to avoid inter-muscular injections.
A unique function that stanozolol(Winstrol) exhibits is its ability to significantly lower SHBG(sex hormone-binding globulin) levels in the body, allowing free testosterone and other AAS the ability to exert anabolic activity in muscle tissues. Stanozolol(Winstrol) displays the exceptional capability of stimulating and facilitating protein synthesis. Stanozolol(Winstrol) possess the capability of boosting collagen synthesis in the body, which is a popular selling feature among those who purchase Stanazol for sale via www.precisionanabolics.com.
Stanozolol’s(Winstrol) chemical structure differs significantly from all androgenic-anabolic steroids(AAS). It contains a 3-2 pyrazole group attached to the first cycloalkane ring(known as the A-ring) of the AAS structure. The pyrazole group’s attachment to the A-ring actually replaces the 3-keto group that normally sits in the same location. Specifically, this major modification classifies stanozolol(Winstrol) as a heterocyclic steroid. This pyrazole group, which is a functional group, is responsible for stanozolol’s(Winstrol) stronger binding affinity for the androgen receptor in muscle tissue. Despite being a DHT-derivative, stanozolol(Winstrol) is active in muscle tissue to a greater degree than DHT itself. DHT is rendered inactive almost immediately by two enzymes upon its entrance into muscle tissue. Stanozolol’s(Winstrol) modifications allow it to avoid immediate metabolization. The pyrazole structure also grants stanozolol(Winstrol) a significant shift in its anabolic and androgenic strength. This shift increases anabolic strength while greatly reducing its androgenic strength.
Stanozolol(Winstrol) possesses a very high binding affinity for SHBG(sex hormone-binding globulin), therefore granting far more free stanozolol(Winstrol) the ability to signal muscle growth. SHBG is a protein that attaches and binds to other sex hormones(testosterone, estrogen, or any synthetic AAS) and renders them useless as long as SHBG is bound to that hormone. SHBG places ‘handcuffs’ on hormones it binds to, and prevents it from functioning. Stanozolol(Winstrol) has demonstrated ability to prevent SHBG from binding with other anabolic steroids, and also demonstrated strong suppression of SHBG production in the body.
Because stanozolol(Winstrol) is a DHT-derivative, it is unable to bind with the aromatase enzyme, which results in no estrogen conversion. Because it does not convert to estrogen, users are able to avoid estrogen-related side-effects, such as water-retention(and the associated risks of elevated blood pressure).